DEPOT MEDROXYPROGESTERONE ACETATE (DMPA) ENHANCES SUSCEPTIBILITY AND INCREASES THE WINDOW OF VULNERABILITY TO HIV-1 IN HUMANIZED MICE

Depot medroxyprogesterone acetate (DMPA) enhances susceptibility and increases the window of vulnerability to HIV-1 in humanized mice

Abstract The Knit Hats progestin-based hormonal contraceptive Depot Medroxyprogesterone Acetate (DMPA) is widely used in sub-Saharan Africa, where HIV-1 is endemic.Meta-analyses have shown that women using DMPA are 40% more likely than women not using hormonal contraceptives to acquire Human Immunodeficiency Virus (HIV-1).Therefore understanding ho

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Late-Onset Startle Syndrome and Obsessive Compulsive Disorder

A case of late onset sporadic startle syndrome in a patient with a right posterior fossa brain tumour is reported.The Clip Light exaggerated startle response did not respond to treatment with clonazepam.In addition to anxiety and depression, the patient developed obsessive- Shorts compulsive symptoms which responded to behavioural therapy.The possi

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Navigating the Uncharted: A Rare Case of Ocular Flutter and Intermittent Jaw Movements in a Case of Chronic Lymphoid Leukemia

Although chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world, neurologic complications arising from direct leukemic involvement of the nervous system are reported in only 1% of patients Body Brush with CLL.Ocular involvement in CLL, direct or indirect, is less known and exceptionally rare.This case involves a 63-year

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Deep-learning-based proxy model for forecasting gas flooding performance of fractured well pattern in tight oil reservoirs

Gas flooding in fractured Diecast Boxes well pattern is a combination of hydraulic fracturing and gas injection to displace reservoir oil within well pattern, and is one of the effective technologies for improving oil recovery in tight and low permeability reservoirs.However, due to the complexity of hydraulic fracturing and multi-phase flow, it be

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